Rosalind and Morris
Goodman Cancer
Institute Principal
Investigators
The Quail lab studies microenvironmental regulation of chronic inflammation and anti-tumour immunity. We use highly-multiplex imaging techniques, spectral flow cytometry and sequencing technologies to study the spatial organization and function of the tumour immune microenvironment at the single-cell level.
What we are
currently
working on
The Quail Lab is focused on the role of the tumour microenvironment during cancer progression, with a particular interest in tumour immunology and myeloid-targeted immunotherapies. Our team is investigating 3 major themes:
- How do chronic inflammatory conditions, such as obesity, promote cancer progression?
- What shapes the immune landscape in tumours, and how does this dictate response to treatment?
- How does the microenvironment affect tumour progression within an immune privileged tissue, such as brain?
To study the tumour microenvironment, we use cutting edge technologies such as highly-multiplexed imaging mass cytometry, intravital microscopy, spectral flow cytometry, single cell sequencing, and genetically-engineered in vivo models.
- Comment le microenvironnement affecte-t-il la progression tumorale au sein d'un tissu immunoprivilegié, tel que le cerveau ? How does the How does the microenvironment affect tumour progression within an immune privileged tissue, such as brain?
- Comment les conditions inflammatoires chroniques, telles que l'obésité, favorisent-elles la progression du cancer ? How do chronic inflammatory conditions, such as obesity, promote cancer progression?
- Quels éléments façonnent le paysage immunitaire dans les tumeurs et comment cela dicte-t-il la réponse au traitement ? What shapes the immune landscape in tumours, and how does this dictate response to treatment?
- Associate Professor
Rosalind and Morris Goodman Cancer Institute
Department of Physiology
Faculty of Medicine and Health Sciences
McGill University - Tier II Canada Research Chair in Tumor Microenvironment research
Our team
Aline Atallah Étudiant.e MDCM-PhD MD/PhD Student 
Valerie Breton Technicien.ne de recherche Research Technician 
Alyssa Cristea Étudiant.e à la maîtrise MSc Student 
Lysanne Desharnais Étudiant.e au doctorat PhD Student 
Benoit Fiset Assistant.e de recherche Research Assistant 
Simon Milette Étudiant au doctorat PhD Student 
Anikka Swaby Étudiant.e au doctorat PhD Student 
Ozgun Varol Étudiant.e au doctorat PhD Student 
Laura Wu Étudiant.e à la maîtrise MSc Student 
Miranda Yu Étudiant.e au doctorat PhD Student
Major discoveries
PublicationsResearch Partners
Get in touch
1160 Pine Avenue W
Montreal, Quebec H3A 1A3
Office: 417
Lab: 411
T. 514-398-2659
T.
F.
daniela.quail@mcgill.ca
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