The Quail Lab is focused on the role of the tumour microenvironment during cancer progression, with a particular interest in tumour immunology and myeloid-targeted immunotherapies. Our team is investigating 3 major themes:
- How do chronic inflammatory conditions, such as obesity, promote cancer progression?
- What shapes the immune landscape in tumours, and how does this dictate response to treatment?
- How does the microenvironment affect tumour progression within an immune privileged tissue, such as brain?
To study the tumour microenvironment, we use cutting edge technologies such as highly-multiplexed imaging mass cytometry, intravital microscopy, spectral flow cytometry, single cell sequencing, and genetically-engineered in vivo models.