Empowering the Next Generation of Cancer Researchers: Summer at the GCI

At the Rosalind and Morris Goodman Cancer Institute (GCI), cancer research doesn’t take a break for summer—and neither does our commitment to training the next generation of scientists.

Each year, the GCI welcomes a dynamic cohort of undergraduate research interns who spend their summers immersed in real-world cancer research. Working alongside leading scientists and graduate trainees, these students gain hands-on experience, develop new skills, and contribute meaningfully to projects in fields ranging from cancer genomics and immunology to metabolism, and bioengineering.

From designing experiments to analyzing data, our undergraduates don’t just observe science—they do it.

“I’m studying the role of antigen-specific regulatory T cells in in vivo mouse models,” says Sophie Courville, a third-year student in Physiology Honours. “This summer, I optimized a protocol to induce naïve CD4+ T cells into regulatory T cells, testing different cytokine concentrations and incubation periods.”

Alongside technical training, students develop a deeper understanding of scientific inquiry and the creative thinking it demands.

Her work focuses on engineering injectable microcubes for controlled drug and vaccine delivery—a promising approach to improving treatment precision and minimizing side effects.

Many students arrive unsure of where to start, but quickly find that curiosity, persistence, and openness go a long way.

“Reach out to professors as early as you can, and be open to any opportunity that comes your way,” says Sophie Courville.

“Read papers from labs you’re interested in,” adds Matthias Calderon, a U3 Biochemistry student working in the Kazak Lab. “It’s okay if you don’t understand everything—what matters is showing genuine curiosity.”

Matthias is using engineered viral vectors to deliver genes into live mice, helping investigate metabolic mechanisms that may prevent obesity-related disease.

“Be ready for your experiments to fail,” says Nicholas Pavlenyi, a recent graduate working in the Siegel Lab on breast cancer metastasis. “Science is slow, but incredibly rewarding. Keep good notes—sometimes the smallest detail becomes a breakthrough.”

Research at the GCI goes beyond the bench. For Krystale Crockett, a Biochemistry major in the Giguère Lab, the experience is shaping his long-term values. “I’ve gained a more sustainable approach to research. I’ve learned how to reduce waste and reuse materials whenever possible.”

Others, like Orchee Haque in the McCaffrey Lab, emphasize how mentorship and teamwork shape the learning experience.

“Don’t be afraid to ask your labmates for help—they have valuable insight. And choose a lab that truly interests you. That passion makes all the difference.”

Orchee is using confocal microscopy to study interactions between epithelial cells and macrophages during early breast cancer progression.

Whether they go on to graduate studies, medical school, or industry, students leave the GCI equipped with technical expertise, critical thinking skills, and a clearer sense of purpose. More than that, they discover that cancer research is not only challenging—it’s human, collaborative, and filled with possibility.

“Every day in the lab makes me feel like I’m building something,” says Xinying Wang. “I’ve learned to stop hesitating and start thinking like a scientist.”